The real tragedy of human existence is not that we are nasty by nature, but that a cruel structural asymmetry grants to rare events of meanness such power to shape our history.
The central idea in The Black Swan is that: rare events cannot be estimated from empirical observation since they are rare.
So the world is much more correlated than we give credit to. And so we see more of what Nassim Taleb calls "black swan events" - rare events happen more often than they should because the world is more correlated.
The real thing that physics tell us about the universe is that it's big, rare event happens all the time — including life — and that doesn't mean it's special.
Adamson feels that drug developers are unreasonably concerned about rare events. The reality is children tolerate phase I therapy new agents being tested to find the best dosage and possible side-effects as well as or better than adults, ... Once the initial studies are done that is, phase I trials in adults study should begin in children.