Egypt is the most populous Arab nation, the seat of Sunni Islamic doctrine, and has tremendous political, religious and social influence on the rest of the region. For better or worse, it will lead the rest of the Middle East by example. So goes Egypt, so goes the region.
The Syrian border town of Qa'im was the main gateway Islamic radicals used to go to Iraq. Syria became the passageway for extremists from Egypt, Libya, Afghanistan, Yemen, Saudi Arabia and other Muslim nations to fight a jihad against American forces in Iraq.
In October 2008, American commandos launched a cross-border raid into Syria to capture an Islamic militant known as Abu Ghadiya. He was accused of being one of al Qaeda in Iraq's main smugglers of fighters and money between Iraq and Syria.
The Muslim Brotherhood, or 'the Brotherhood' for short, is an Islamic group founded in Egypt in 1928. It has been pursuing a secret campaign to take over the government since its creation.
For eight years, you had the Bush administration with a very interventionist policy, driving into world affairs, driving primarily into the Islamic world, army first or fist first.
Anyone who follows the Middle East and Islamic world in general can't deny it is often a very violent place, that a band of instability now stretches from Algeria to Pakistan.