It's important that patients not assume that the hormones of pregnancy are going to protect them from the types of problems they've had with mood previously.
We found that patients who stopped their antidepressant during pregnancy were five times more likely to have a return of depressive symptoms than those patients who had decided to continue (them) during pregnancy.
Clinical lore has held for decades that pregnancy protected women from mood disorders. What drove this study was a divergence between that belief and what many of us were seeing clinically, that many women who stopped using antidepressants during pregnancy appeared to be relapsing.