Proteins Quotations
Proteins Quotes from:
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Otherwise Quotes
Genes are effectively one-dimensional. If you write down the sequence of A, C, G and T, that's kind of what you need to know about that gene. But proteins are three-dimensional. They have to be because we are three-dimensional, and we're made of those proteins. Otherwise we'd all sort of be linear, unimaginably weird creatures.
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Absolutely Quotes
Until now we have not had a close-up view of the precise surface where the two proteins interact. That surface is absolutely crucial in permitting the parasite to enter the cell. If we can determine its features in atomic detail, we may be able to find weak points that could make good targets for drugs.
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Biologists Quotes
Mathematicians have been hiding and writing messages in the genetic code for a long time, but it's clear they were mathematicians and not biologists because, if you write long messages with the code that the mathematicians developed, it would more than likely lead to new proteins being synthesized with unknown functions.
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Against Quotes
Like we handle antibodies against foreign proteins and we only get viruses like measles and chicken pox once, you can form antibodies against hundreds of things on the cells, ... The future is going tobe the development of those targeted therapies so that we will evaluate cancer cells in a much different way. We will do enzyme profiles and protein profiles to come up with almost a blueprint of the cancer and pick and choose those things that are available.
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Alley Quotes
Using HPRD and several other databases, we have been able to develop a gold mine of new information for researchers seeking new ways of finding candidate genes involved in genetic diseases. And our demonstration that a protein's importance is not based on the number of interactions it has with other proteins is an important conceptual breakthrough. It eliminates a blind alley that could mislead researchers investigating the roles of specific proteins in the cell.
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Chinese Quotes
We see the potential for a production vehicle with tremendous flexibility, which is a real alternative to Chinese hamster ovaries, the current industry standard. We have set ourselves a target of 25% of all new proteins and monoclonal antibodies. For anything in development and reaching the market between 2015 and 2020, we want 25% of the production platform to be PER.C6.
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Active Quotes
For a decade, I had been studying a transparent worm, the C. elegans. I immediately thought, if you could put the G.F.P. gene into C. elegans, you'd then be able to see biological processes in live animals. Until then, we had to kill them and prepare their tissues chemically to visualize proteins or active genes within cells.
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Beyond Quotes
ChIP-on-chip goes beyond gene expression to explore gene regulation activity. Regulatory proteins bind to genomic DNA to control DNA replication and gene expression, thereby functioning as switches in the regulatory circuitry of cells. Combine this information with gene expression data and you get biomarkers.
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Ability Quotes
Genes are important because they are the blueprints for proteins, but proteins are where the action is in human life and health. This ability to find links between sets of proteins involved in different genetic disorders offers a novel approach for more rapidly identifying new candidate genes involved in human diseases.