I believe whatever smart, ambitious people are working on will be the trend of the future. I do think that it's worth thinking critically about what the future will be.
I always tell my partners that our job is to fund all the companies we can that can be worth $10 billion or more. That's such a difficult constraint, we can't have any other constraints.
Companies generally work better when they are smaller. It's always worth spending time to think about the least amount of projects/work you can feasibly do, and then having as small a team as possible to do it.