These guys hit a lot. They can change the score like that. All you have to do is hold them in the game, keep the score close, that's what I've done the last couple times.
Early in your career you have to learn that even if you give up four, five home runs you've got to keep pitching the game. If you feel bad or mad, you have to finish the game no matter what happens. The game is yours until the last out you have.