I'd really love to work with virtual reality at some point. You could make a killer adventure game with that.
There are now college degrees in game design and interactive media, so if I were starting now, I would probably do that. When I started, you had to break into design from QA or programming or art, but it's really not true anymore.
Story may not be a great addition to some games - games where action is the whole reason for the game to exist.